doc. RNDr. Lucie BRULÍKOVÁ, Ph.D.
Telefon:
585634464
E-mail:
Pracoviště:
Katedra organické chemie
Org. jednotka:
Přírodovědecká fakulta
Adresa:
17. listopadu 12
Místnost:
3.019
Pracovní zařazení:
docent - proděkanka
ČLÁNEK
Chasák J., Brulíková L.
Solid-phase synthesis of aryl squaramides using Liebeskind–Srogl cross-coupling.
RSC Advances.
2025.
Chasák J., Janicki I., Brulíková L.
The Liebeskind–Srogl cross-coupling reaction towards the synthesis of biologically active compounds.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.
2025.
Kolařík M., Ilbeigi K., Caljon G., Brulíková L.
Thiazolidinones and related analogues as efficient antitrypanosomal agents.
Bioorganic and Medicinal Chemistry.
2025.
Chasák J., Van Moll L., Matheeussen A., De Vooght L., Cos P., Brulíková L.
The Liebeskind–Srogl Cross-Coupling Reaction as a Crucial Step in the Synthesis of New Squaramide-Based Antituberculosis Agents.
ACS Omega.
2024.
Šlachtová V., Casaretto N., Brulíková L., Six Y.
Bicyclic N-dihalocyclopropylamide derivatives as precursors of nitrogen-containing fused polycyclic systems.
Organic and Biomolecular Chemistry.
2023.
Chasák J., Oorts L., Dak M., Šlachtová V., Bazgier V., Berka K., Brulíková L.
Expanding the squaramide library as mycobacterial ATP synthase inhibitors: innovative synthetic pathway and biological evaluation.
Bioorganic and Medicinal Chemistry.
2023.
Dak M., Šlachtová V., Šebela M., Bazgier V., Berka K., Brulíková L.
Novel heterocyclic hydroxamates as inhibitors of the mycobacterial zinc metalloprotease Zmp1 to probe its mechanism of function.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.
2022.
Chasák J., Brulíková L.
Polymer-supported synthesis of various pteridinones and pyrimidodiazepinones.
MOLECULES.
2021.
Urban M., Šlachtová V., Brulíková L.
Small organic molecules targeting the energy metabolism of Mycobacterium tuberculosis.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.
2021.
Chasák J., Šlachtová V., Urban M., Brulíková L.
Squaric acid analogues in medicinal chemistry.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.
2021.
Brulíková L., Volná T., Hlaváč J.
Bis-Rhodamine B System as a Tin Detector or Molecular Electronics Device.
ACS Omega.
2020.
Šlachtová V., Šebela M., Torfs E., Oorts L., Cappoen D., Berka K., Bazgier V., Brulíková L.
Novel thiazolidinedione-hydroxamates as inhibitors of Mycobacterium tuberculosis virulence factor Zmp1.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.
2020.
Machníková R., Janovská L., Brulíková L.
Solid-phase synthetic approach towards new pyrimidines as potential antibacterial agents.
JOURNAL OF MOLECULAR STRUCTURE.
2020.
Šlachtová V., Janovská L., Brulíková L.
Solid-phase synthesis Pyrimidine Thiazolidinedione Conjugates Antimycobacterial Antibacterial.
JOURNAL OF MOLECULAR STRUCTURE.
2019.
Šlachtová V., Chasák J., Brulíková L.
Synthesis of various 2-aminobenzoxazoles: the study of cyclization and Smiles rearrangement.
ACS Omega.
2019.
Šlachtová V., Brulíková L.
Benzoxazole Derivatives as Promising Antitubercular Agents.
ChemistrySelect.
2018.
Petráček M., Brulíková L., Motyka K., Hlaváč J.
From Study of Catalytic Hydrogenation to Novel Ratiometric pH Indicators with Quinoline Scaffold.
ChemistrySelect.
2017.
Mejdrová I., Brulíková L., Volná T., Hlaváč J.
Regioselective synthesis of 5-[(2,3-dihydroxypropoxy)methyl]uracil analogues.
New Journal of Chemistry.
2017.
Brulíková L., Okorochenkova Y., Hlaváč J.
A solid-phase synthetic approach to pHindependent rhodamine-type fluorophores.
Organic & Biomolecular Chemistry.
2016.
Brulíková L., Harrison AN., Miller MJ., Hlaváč J.
Stereo- and regioselectivity of the hetero-Diels–Alder reaction of nitroso derivatives with conjugated dienes.
Beilstein Journal of Organic Chemistry.
2016.
Brulíková L., Křupková S., Labora M., Motyka K., Hradilová L., Mistrík M., Bártek J., Hlaváč J.
Synthesis and study of novel pH-independent fluorescent mitochondrial labels based on Rhodamine B.
RSC Advances (online).
2016.
Brulíková L., Hlaváč J., Hradil P.
DNA interstrand cross-linking agents and their chemotherapeutic potential.
Current Medicinal Chemistry.
2012.
Vaňková B., Brulíková L., Wu B., Krchňák V.
Synthesis of Piperazinones, Piperazines, Tetrahydropyrazines, and Dihydropyrazinones from Polymer-Supported Acyclic Intermediates via N-Alkyl- and N-Acyliminiums.
European Journal of Organic Chemistry.
2012.
BRULÍKOVÁ L., DŽUBÁK P., HAJDÚCH M., HLAVÁČ J.
Synthesis of Various 5-Alkoxymethyluracil Analogues and Structure-Cytotoxic Activity Relationship Study.
Carbohydrate Research.
2011.
BRULÍKOVÁ L., HLAVÁČ J.
Synthesis, reactivity and biological activity of 5-alkoxymethyluracil analogues.
Beilstein Journal of Organic Chemistry.
2011.
Andersen N., Chandak N., Brulíková L., Kumar P., Jensen M., Jensen F., Sharma P., Nielsen P.
Efficient RNA-targeting by the introduction of aromatic stacking in the duplex major groove via 5-(1-phenyl-1,2,3-triazol-4-yl)-2′-deoxyuridines.
Bioorganic & Medicinal Chemistry.
2010.
Brulíková L., Džubák P., Hajdúch M., Lachnitová L., Kollareddy M., Kolář M., Bogdanová K., Hlaváč J.
Synthesis of 5-[alkoxy-(4-nitro-phenyl)-methyl]-uridines and study of their cytotoxic activity.
European Journal of Medicinal Chemistry.
2010.
PATENT, UŽITNÝ VZOR, PRŮMYSLOVÝ VZOR
Brulíková L., Hlaváč J., Motyka K.
Fluorescenční sonda rhodamino-pyrimidinového typu pro stanovení dusitanů ve vodě.
2013.
Brulíková L., Motyka K., Hlaváč J.
Fluorescenční sonda rhodamino-pyrimidinového typu pro stanovení pH.
2012.
ABSTRAKT
Brulíková L., Nielsen P.
Synthesis of 2´-deoxy-uridine analogues by the alkyne-azide "click" reaction and their influence on the duplex stability.
Chemické listy.
2008.
HABILITAČNÍ PRÁCE
Brulíková L.
Development of novel antituberculosis agents.
2022.
Aktuálně vyučované předměty
| název předmětu | katedra/zkratka | semestr | typ | hodin |
|---|---|---|---|---|
| Kapitoly z bioorganické chemie | OCH/KBCH | LS | Př | 3 |
| Bioorganická chemie | OCH/BIOR1 | ZS | Př | 2 |
| Bioorganická chemie | OCH/BIOR1 | ZS | Se | 2 |