doc. RNDr. Lucie BRULÍKOVÁ, Ph.D.

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585634464

Katedra organické chemie

Přírodovědecká fakulta

17. listopadu 12

3.019

docent - proděkanka

ČLÁNEK
Chasák J., Janicki I., Brulíková L. The Liebeskind–Srogl cross-coupling reaction towards the synthesis of biologically active compounds. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2025.
Kolařík M., Ilbeigi K., Caljon G., Brulíková L. Thiazolidinones and related analogues as efficient antitrypanosomal agents. Bioorganic and Medicinal Chemistry. 2025.
Chasák J., Van Moll L., Matheeussen A., De Vooght L., Cos P., Brulíková L. The Liebeskind–Srogl Cross-Coupling Reaction as a Crucial Step in the Synthesis of New Squaramide-Based Antituberculosis Agents. ACS Omega. 2024.
Šlachtová V., Casaretto N., Brulíková L., Six Y. Bicyclic N-dihalocyclopropylamide derivatives as precursors of nitrogen-containing fused polycyclic systems. Organic and Biomolecular Chemistry. 2023.
Chasák J., Oorts L., Dak M., Šlachtová V., Bazgier V., Berka K., Brulíková L. Expanding the squaramide library as mycobacterial ATP synthase inhibitors: innovative synthetic pathway and biological evaluation. Bioorganic and Medicinal Chemistry. 2023.
Dak M., Šlachtová V., Šebela M., Bazgier V., Berka K., Brulíková L. Novel heterocyclic hydroxamates as inhibitors of the mycobacterial zinc metalloprotease Zmp1 to probe its mechanism of function. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2022.
Urban M., Šlachtová V., Brulíková L. Small organic molecules targeting the energy metabolism of Mycobacterium tuberculosis. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2021.
Chasák J., Šlachtová V., Urban M., Brulíková L. Squaric acid analogues in medicinal chemistry. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2021.
Brulíková L., Volná T., Hlaváč J. Bis-Rhodamine B System as a Tin Detector or Molecular Electronics Device. ACS Omega. 2020.
Šlachtová V., Šebela M., Torfs E., Oorts L., Cappoen D., Berka K., Bazgier V., Brulíková L. Novel thiazolidinedione-hydroxamates as inhibitors of Mycobacterium tuberculosis virulence factor Zmp1. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2020.
Machníková R., Janovská L., Brulíková L. Solid-phase synthetic approach towards new pyrimidines as potential antibacterial agents. JOURNAL OF MOLECULAR STRUCTURE. 2020.
Šlachtová V., Janovská L., Brulíková L. Solid-phase synthesis Pyrimidine Thiazolidinedione Conjugates Antimycobacterial Antibacterial. JOURNAL OF MOLECULAR STRUCTURE. 2019.
Šlachtová V., Brulíková L. Benzoxazole Derivatives as Promising Antitubercular Agents. ChemistrySelect. 2018.
Petráček M., Brulíková L., Motyka K., Hlaváč J. From Study of Catalytic Hydrogenation to Novel Ratiometric pH Indicators with Quinoline Scaffold. ChemistrySelect. 2017.
Mejdrová I., Brulíková L., Volná T., Hlaváč J. Regioselective synthesis of 5-[(2,3-dihydroxypropoxy)methyl]uracil analogues. New Journal of Chemistry. 2017.
Brulíková L., Okorochenkova Y., Hlaváč J. A solid-phase synthetic approach to pHindependent rhodamine-type fluorophores. Organic & Biomolecular Chemistry. 2016.
Brulíková L., Harrison AN., Miller MJ., Hlaváč J. Stereo- and regioselectivity of the hetero-Diels–Alder reaction of nitroso derivatives with conjugated dienes. Beilstein Journal of Organic Chemistry. 2016.
Brulíková L., Křupková S., Labora M., Motyka K., Hradilová L., Mistrík M., Bártek J., Hlaváč J. Synthesis and study of novel pH-independent fluorescent mitochondrial labels based on Rhodamine B. RSC Advances (online). 2016.
Brulíková L., Hlaváč J., Hradil P. DNA interstrand cross-linking agents and their chemotherapeutic potential. Current Medicinal Chemistry. 2012.
BRULÍKOVÁ L., DŽUBÁK P., HAJDÚCH M., HLAVÁČ J. Synthesis of Various 5-Alkoxymethyluracil Analogues and Structure-Cytotoxic Activity Relationship Study. Carbohydrate Research. 2011.
BRULÍKOVÁ L., HLAVÁČ J. Synthesis, reactivity and biological activity of 5-alkoxymethyluracil analogues. Beilstein Journal of Organic Chemistry. 2011.
Andersen N., Chandak N., Brulíková L., Kumar P., Jensen M., Jensen F., Sharma P., Nielsen P. Efficient RNA-targeting by the introduction of aromatic stacking in the duplex major groove via 5-(1-phenyl-1,2,3-triazol-4-yl)-2′-deoxyuridines. Bioorganic & Medicinal Chemistry. 2010.
Brulíková L., Džubák P., Hajdúch M., Lachnitová L., Kollareddy M., Kolář M., Bogdanová K., Hlaváč J. Synthesis of 5-[alkoxy-(4-nitro-phenyl)-methyl]-uridines and study of their cytotoxic activity. European Journal of Medicinal Chemistry. 2010.
PATENT, UŽITNÝ VZOR, PRŮMYSLOVÝ VZOR
HABILITAČNÍ PRÁCE
Current courses
Course title Department/Abbrev. Semester Type Classes
Lectures in Biooganic Chemistry OCH/KBCH LS 3
Bioorganic Chemistry OCH/BIOR1 ZS 2
Bioorganic Chemistry OCH/BIOR1 ZS Se 2

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